Monday 28 November 2011

Hypoactivity in a newborn

You were called to normal nursery unit to evaluate a 24 hours old full term female newborn for a major concern of hypoactivity. Baby was born by normal vaginal delivery to a 42 year old, G1P0, rubella and toxo immune, HBsAg negative, GBS positive mother. Mother received 2 doses of Pen G prior to delivery. Over the last 6 hours, baby received only a 2 minutes breastfeeding because of inability to catch the nipple. Baby didn't pass urine for the last 10 hours. PE: HR 160, BP 65/40(55), T 37, RR 50, SaO2=96%. Physical exam is remarkable for diminished skin turgor otherwise normal. What's your most probable diagnosis?
  • Sepsis versus congenital heart disease
  • Sepsis versus hypovolemia due to inadequate feeding
  • Sepsis versus hypovolemia due to intracranial bleeding